Early bone marrow conversion in adolescents with Anorexia Nervosa: A T1 Relaxometry Study
نویسندگان
چکیده
Introduction: T1-weighted imaging of the knees of adolescent girls with anorexia nervosa (AN) has been found to show consistently higher signal intensity and greater homogeneity in the femur and tibia as compared to normal adolescents, who typically exhibit striations and regions of lower signal, representing hematopoietic marrow. We performed T1 relaxometry measurements on a cohort of adolescent girls with AN as well as age-matched controls to study this phenomenon. The use of an extremity scanner led to higher subject recruitment rates since the patient population with AN tend to have high rates of anxiety and claustrophobia.
منابع مشابه
Bone Marrow Changes in Adolescent Girls With Anorexia Nervosa
Early osteoporosis is common among adolescent girls with anorexia nervosa (AN) and may result from premature conversion of red (RM) to yellow bone marrow. We performed right knee magnetic resonance imaging (MRI) on a 1.0 T extremity scanner in 20 patients and 20 healthy controls, aged 16.2 +/- 1.6 years (mean +/- SD). Coronal T(1)-weighted (T(1)W) images and T(1) maps were generated from T(1) r...
متن کاملGelatinous degeneration of the bone marrow in anorexia nervosa.
Anorexia nervosa is a chronic psychiatric process characterized by a restrictive disorder in alimentary habits. Hematologic alterations in the peripheral blood include cytopenias involving one or more hematopoietic lineages. Morphologic changes in the bone marrow and stereologic alterations in bone marrow adiopocytes may also be observed in anorexia nervosa. We present a 12-year-old girl who ha...
متن کاملAnorexia nervosa and bone.
Anorexia nervosa (AN) is a condition of severe low weight that is associated with low bone mass, impaired bone structure, and reduced bone strength, all of which contribute to increased fracture risk. Adolescents with AN have decreased rates of bone accrual compared with normal-weight controls, raising additional concerns of suboptimal peak bone mass and future bone health in this age group. Ch...
متن کاملA child with anorexia nervosa presenting with severe infection with cytopenia and hemophagocytosis: a case report
BACKGROUND Patients with anorexia nervosa in the acute phase have physical complications, such as infectious disease. Although hemophagocytic syndrome due to infection is a rare complication in anorexia nervosa, early identification for hemophagocytosis is important for avoiding a life-threatening condition. CASE PRESENTATION We report a case of a 12-year-old girl with anorexia nervosa presen...
متن کاملMedical complications in adolescents with anorexia nervosa: a review of the literature.
The purpose of the current article is to summarize the evidence-based medical complications and treatments that are both common and unique to adolescents with anorexia nervosa (AN). Recent literature relating to the cardiovascular complications, refeeding syndrome, alterations in linear growth, impaired bone mineral accretion, and structural and functional brain changes was reviewed. The litera...
متن کامل